Home Tools
Log in
Cart

Search Result

Search Results for " chronic neuropathic pain "

12

Compounds

Cat No. Product Name Synonyms Targets
T7416 WS-12 TRP/TRPV Channel
WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)
T8333 Aurintricarboxylic acid ATA,NSC-4056,NSC4056,NSC 4056 Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.
T31208 Dasolampanel NGX-426,NGX 426,NGX426 GluR , iGluR
Dasolampanel (NGX-426) is an orally available ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders, including neuropathic pain and migraine.
T34308 Rezatomidine AGN-203818,AGN203818,AGN 203818 Adrenergic Receptor
Rezatomidine (AGN203818) is a selective antagonist of α2-adrenergic receptor and can be used in studies about chronic pain, including neuropathic pain.
T3699 Bay 59-3074 Cannabinoid Receptor
Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM). In rat models of chronic neuropathic and inflammatory pain, it displays anti-hyperalgesic and antiallodynic properties.
T32722 Lexanopadol GRT-13106G,GRT6006,GRT 13106G,GRT-6006,GRT 6006,GRT13106G
Lexanopadol (GRT6006) is a potent ORL-1 agonist (opioid receptor-like-1), suitable for the treatment of moderate to severe chronic pain, including neuropathic pain.
T28106 MRS5698 MRS 5698,MRS-5698
MRS5698 is a high affinity and selective agonist of A3 adenosine receptor (Ki ~ 3 nM) protects against chronic neuropathic pain. MRS5698 displays >1000-fold selectivity over A1 and A2A adenosine receptors
TQ0002L A-317491 sodium A-317491,A 317491,A317491
A-317491 is an effective selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, which reverses inflammatory mechanical hyperalgesia and relieves chronic inflammation and neuropathic pain in rats by acting on p...
T74739 Oleoyl-D-lysine
Oleoyl-D-lysine, a lipid-based selective Glycine Transporter-2 (GlyT2) inhibitor, effectively reverses neuropathic pain and exhibits an antidrowsiness effect in mice with chronic neuropathic pain. It is considered safe a...
T68297 Dilmapimod tosylate
Dilmapimod tosylate is a potent p38 mitogen-activated protein kinase (MAPK) inhibitor. It was investigated for its anti-inflammatory effect in non-head injury trauma patients at risk for developing acute respiratory dist...
T79373 A3AR agonist 2 Adenosine Receptor
Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM. This compound is utilized in research pertaining to inflammato...
T80074 Biphalin TFA Others
Biphalin TFA is an opioid peptide analog that penetrates the blood-brain barrier (BBB) and encompasses two active enkephalin pharmacophores. It exhibits high affinity for opioid receptors and demonstrates analgesic effec...
TargetMol